Prescription Medicine

Serious Drug Interaction Discovered: Ceftriaxone/Rocephin and Lansoprazole/Prevacid

A recent article in the Journal of the American College of Cardiology on October 11, 2016 reveals concurrent use of Lansoprazole (brand name Prevacid), a proton-pump inhibitor, and ), a cephalosporin antibiotic, may increase the risk of acquired long QT syndrome (LQTS), a life-threatening arrhythmia.

The author notes that “QT-DDI’s (QT drug-drug interactions) are not routinely evaluated pre-clinically and can go undiscovered […]